Frozen fish versus cell cryopreservation: What’s the difference?

Fish Stick ParadoxUnlike samples in the biopharmaceutical industry, frozen food (think frozen fish) must adhere to strict regulations for how it is routinely frozen, stored, and shipped.

The wider scientific community accepts there is a glass transition temperature at -135° C. It is generally beneficial to ensure that biological material – once cryogenically frozen – does not experience even transient periods above this temperature.

Above the glass transition temperature, cryo-preserved biological or cellular material can be damaged. As with frozen food products, it’s not just the time spent above a target temperature (-135°C) that matters – it is also the number of times the material changes temperature.

Regenerative medicine research and clinical applications will revolutionize medical care. But researchers and point-of-care centers will need to design a cryogenic eco-system to support the various products shelf life at < -135°C. This model will need to scale to meet future demand as reliance on these therapies increases.

Learn more about critical cold-chain considerations – and the tools and resources that will help you eliminate product variability and improve outcomes.

Download the slidecast to learn more.